The virus (for lack if a better term) that destroyed the gods was not of this world. It was found in the outer reaches of the universe by one forgotten god, modified and unleashed.
The virus was inimical to the stuff that the gods were made of. Not matter per se, as the gods were never truly material in the way we think of it, but they did have a real substance to them. Not anymore, they were utterly unmade.
The virus' effect on other things is less predictable. Magic is similar to the power of the gods, but not identical. Thus magic carries the virus, but is not destroyed by it. In fact, the virus itself being made up of an incredibly powerful and strange energy, magic was in many ways made stronger, if far more dangerous.
As for mortal flesh, life on this world was altered drastically by the gods, and infused with a portion of their power and essence. Thus, the virus is almost always inimical to it. But unlike the gods, who were helpless before it, mortals are made of different stuff that gives them strengths and options that the gods did not have. Thus usually they are unmade, but sometimes they are only changed.
Work on making Blood-touched mutations and changes more Lovecraftian in tone than straight up undeath, at least in its greater forms.
I keep thinking I should come up with names for this stuff - the blood, the virus, the dead gods, etc. But I kind of like having the stuff unnamed. The names of the gods have been deliberately forgotten. Nobody understands the virus or even know it exists really, so it just the blood as far as they know.
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